The Psychopathology and Allostatic load across the Life Span (PALS) network is a network of international academic centers that have come together to transform windows of vulnerability to mental and physical disorders into windows of neuroscientific advancement with diagnostic and therapeutic implications.
To view the full mission statement, click here. To learn more about the aims and goals of PALS, the different academic sites, and current events and projects, please explore the tabs located in the sidebar.
April 2019 - Check out Dr. Sophia Frangou and Dr. Andrew McIntosh's paper on "Insulin Resistance; Geentic associations with depression and cognition in population based cohorts," published in Experimental Neurology.
"Insulin resistance, broadly defined as the reduced ability of insulin to exert its biological action, has been associated with depression and cognitive dysfunction in observational studies. However, it is unclear whether these associations are causal and whether they might be underpinned by other shared factors."
Click here to read the full paper.
January 2019 - Congratulations to Dr. Nasca et al for their article in Experimental Neurology on "Childhood trauma and insulin resistance in patients suffering from depressive disorders."
Click here to see the accepted manuscript. Stay tuned for the final version!
April 2019: Drs. Tomasik, Lago and Vazquez-Bourgon have published a research letter on "Association of Insulin Resistance with Schizophrenia Polygenic Risk Score and Response to Antipsychotic Treatment. Read the full letter here.
August 2018: We are excited to announce that, under Dr. Nemeroff's leadership, Dell Med is launching the Institute for Early Life Adversity Research as part of the Mulva Clinic for the Neurosciences.