Gestational Diabetes Study
Funding: Pritzker Neuropsychiatric Disorders Research Consortium
PIs: Dr. Rasgon, Dr. Reagan, Dr. Tamashiro, Dr. Nasca
Aims: The main purpose of this proposal is to describe biomarkers of neuroinflammation (IR) and allostatic load (telomeres, CrAt, and LAC deficiency) associated with GDM and its protential programming effect on initial (newborn) telomere length across species. Following animal data of high fat diet influencing weight gain in pregnant dams, we will attempt to dissociate effects of obesity vs. IR on biomarkers of allostatic load and behavioral correlates in women and their neonates.