Insulin resistance doubles risk of major depressive disorder, Stanford study finds
Link: https://stan.md/3zF3wEL
Published online September 2021 in Stanford Medicine News
Insulin resistance: Genetic associations with depression and cognition in population based cohorts
Authors: Sophia Frangou, Masoud Shirali, Mark J. Adams, David M. Howard, Jude Gibson, Lynsey S. Hall, Blair H. Smith, Sandosh Padmanabhan, Alison D. Murray, David J. Porteous, Chris S. Haley, Ian J. Deary, Toni-Kim Clarke, Andrew M. McIntosh
Published online June 2019 in Experimental Neurology
Childhood trauma and insulin resistance in patients suffering from depressive disorders
Authors: Carla Nasca, Kathleen Watson-Lin, Benedetta Bigio, Thalia K. Robakis, Alison Myoraku, Tonita E. Wroolie, Bruce S. McEwen, Natalie Rasgon
Published online March 2019 in Experimental Neurology
Early life adversity blunts responses to pioglitazone in depressed, overweight adults
Authors: Thalia K. Robakis, Kathleen Watson-Lin, Tonita E. Wroolie, Alison Myoraku, Carla Nasca, Benedetta Bigio, Bruce McEwen, Natalie L. Rasgon
Published online January 2019 in European Psychiatry
Brain and behavioral correlates of insulin resistance in youth with depression and obesity
Authors: Manpreet K. Singh, Sara M. Leslie, Mary Melissa Packer, Yevgeniya V. Zaiko, Owen R. Phillips, Elizabeth Weisman, Danielle Wall, Booil Jo, Natalie L. Rasgon
Accepted on March 26, 2018 in Hormones and Behavior
Multivariate Associations Among Behavioral, Clinical, and Multimodal Imaging Phenotypes in Patients With Psychosis
Authors: Dominik A. Moser, Gaelle E. Doucet, Won Hee Lee, Alexander Rasgon, Hannah Krinsky, Evan Leibu, Alex Ing, Gunter Schumann, Natalie Rasgon, Sophia Frangou
Published online March 7, 2018 in JAMA Psychiatry
Depression and obesity: evidence of shared biological mechanisms
Authors: Yuri Milaneschi, W. Kyle Simmons, Elisabeth F. C. van Rossum, Brenda WJH Penninx
Published online February 16, 2018 in Molecular Psychiatry
Determinants of cognitive function in adults with Type 2 Diabetes Mellitus: A meta-analysis
Authors: Mansur, R., Rasgon, N., Yena, L., Zhou, A., Rosenblat, J., Bruins, R.,...McIntyre, R.
Published online February 30, 2018 in Annals of Clinical Psychiatry
An Integrated Brain-Behavior Model for Working Memory
Authors: D A Moser, G E Doucet, A Ing, D Dima, G Schumann, R M Bilder, S Frangou
Published online December 5, 2017 in Molecular Psychiatry
Insulin Resistance, an unmasked culprit in depressive disorder: Promises for intervention
Authors: Kathleen Watson, Carla Nasca, Linn Aasly, Bruce McEwen, Natalie Rasgon
Published online: November 26, 2017 in Neuropharmacology
Roles of Inflammation and Depression in the Development of Gestational Diabetes
Authors: Thalia Robakis, Linn Aasly, Katherine Williams, Claire Clark, Natalie Rasgon
Published online October 28, 2017 in Current Behavioral Neuroscience Reports
Treatment with a GLP-1R agonist over four weeks promotes weight loss-moderated changes in frontal-striatal brain structures in individuals with mood disorders
Authors: Mansur RB, Zugman A, Ahmed J, Cha DS,Subramaniapillai M, Lee Y, Lovshin J, Lee JG, Lee J, Drobinin V, Newport J, Brietzke E, Reininghaus EZ, Sim K, Vinbery B, Rasgon N, Hajek T, McIntyre RS.
Published September 1, 2017 in European Neuropsychopharmacology
Telomere length and bipolar disorder
Authors: Powell T, Danai D, Frangou S, Breen G
Accepted: June 2017 in Neuropsychopharmacology
Obesity/hyperleptinemic phenotype impairs structural and functional plasticity in the rat hippocampus
Authors: Grillo CA, Pirolo GG, Junor L, Wilson SP, Mott DD, Wilson MA, Reagan LP
Published: February 2011 in Physiology and Behavior
Memory Impairment in Obese Zucker Rats: An Investigation of Cognitive Function in an Animal Model of Insulin Resistance and Obesity
Authors: Winocur G, Greenwood CE, Piroli GG, Grillo CA, Reznikov LR, Reagan LP, McEwen BS
Published: 2005 in Behavioral Neuroscience
Hippocampal insulin resistance and cognitive dysfunction
Authors: Geert JB and Reagan LP
Published: November 2015 in Nature
Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity
Authors: Grillo CA, Piroli GG, Lawrence RC, Wrighten SA, Green AJ, Wilson SP, Sakai RR, Kelly SJ, Wilson MA, Mott DD, Reagan LP
Published: 2015 in Diabetes
Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood.
Authors: Heim C, Newport DJ, Heit S, Graham YP, Wilcox M, Bonsall R, Miller AH, Nemeroff CB
Published: August 2000 in JAMA Psychiatry
Influence of child abuse on adult depression: moderation by the corticotropic-releasing hormone receptor gene.
Authors: Bradly RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W, Gillespie CF, Berg T, Evces M, Newport DJ, Stowe ZN, Heim CM, Nemeroff CB, Schwartz A, Cubells JF, Ressler KJ
Published: February 2008 in Archives of General Psychiatry
Differential functional connectivity within an emotion regulation neural network among individuals resilient and suspectible to the depressogenic effects of early life stress.
Authors: Cisler JM, James GA, Tripathi S, Mletzko T, Heim C, Hu XP, Mayberg HS, Nemeroff CB, Kilts CD.
Published: March 2013 in Psychological Medicine
Metabolic syndrome, major depression, generalized anxiety disorder, and ten-year all-cause and cardiovascular mortality in middle aged and elderly patients.
Authors: Butnoriene J, Bunevicius A, Saudargiene A, Nemeroff CB, Norkus A, Ciceniene V, Bunevicius R.
Published: 2015 in the International Journal of Cardiology
http://www.sciencedirect.com/science/article/pii/S0167527315008451
Paradise Lost: The Neurobiological and Clinical Consequences of Child Abuse and Neglect
Authors: Nemeroff CB
Published: March 2, 2016 in Neuron
http://www.sciencedirect.com/science/article/pii/S0896627316000209
Childhood trauma predicts antidepressant response in adults with major depression: data from the randomized international study to predict optimized treatment for depression.
Authors: Williams LM, Debattista C, Duchemin AM, Schatzbergy AF, Nemeroff CB.
Published: May 3, 2016 in Translational Psychiatry
Elevated Body Mass Index is associated with increased integration and reduced cohesion of sensory-driven and internally-guided resting-state functional brain networks
Authors: Doucet GE, Rasgon N, McEwen BS, Micali N, Frangou S
Published: January 23, 2017 in Cerebral Cortex
The Brain and Body on Stress: Allostatic Load and Mechanisms for Depression and Dementia
Authors: McEwen BS, Rasgon N
Published: November 2013 in Perspectives on Psychological Science
Insulin Resistance: A Missing Link No More
Authors: Rasgon N, McEwen BS
Published: October 4, 2016 in Molecular Psychiatry
http://www.nature.com/mp/journal/v21/n12/full/mp2016162a.html
Adjuvant pioglitazone for unremitted depression: Clinical correlates of treatment response
Authors: Rasgon N, Wroolie T, Watson K, Robakis, T
Published: October 22, 2015 in Psychiatry Research
Telomere length as a predictor of response to Pioglitazone in patients with unremitted depression: a preliminary study
Authors: Rasgon N, Lin KW, Lin J, Epel E, and Blackburn E
Published: January 5 2016 in Translational Psychiatry
Liraglutide promotes improvements in objective measures of cognitive dysfunction in individuals with mood disorders: A pilot, open-label study
Authors: Mansur RB, Ahmed J, Cha DS, Woldeyohannes HO, Subramaniapillai M, Lovshin J, Lee JG, Lee JH, Brietzke E, Reininghaus EZ, Sim K, Vinberg M, Rasgon N, Hajek T, McIntyre RS
Published: January 1, 2017 in Journal of Affective Disorders
A randomized, double-blind, controlled trial evaluating the effect of intranasal insulin on neurocognitive function in euthymic patients with bipolar disorder
Authors: McIntyre RS, Soczynska JK, Woldeyohannes HO, Miranda A, Vaccarino A, MacQueen G, Lewis GF, Kennedy SH
Published: November, 2012 in Bipolar Disorders
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